Serenity (2005)
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The crew of the ship Serenity try to evade an assassin sent to recapture telepath River.
Storyline
Serenity continues the story of the TV series it was based upon ("Firefly"). River Tam had a secret - one in which she's not even aware - so dangerous, no one's safe, as an Alliance operative's sent to capture her, and all others are considered irrelevant to his job.